Department of Pharmacology

Introduction: -

The Department of Pharmacology was established in the year 2011 under the headship of Professor (Dr.) Harihar Dikshit. In a short journey of 8 years the Department of Pharmacology was raised from dust to one of the most well-equipped department of this prestigious institute of the state.

Department of Pharmacology is actively involved in training 2nd Prof. MBBS, MD-Pharmacology, PhD Pharmacology, BSc Nursing and BSc MLT students in both theoretical as well as practical aspects of pharmacology. The theoretical aspects are supplemented by technological innovations in teaching pharmacology. A simulation laboratory for demonstrating the effects of drugs on in-vivo & in-vitro models using computers is functional. The laboratory has the infrastructure, software and hardware in place for training MBBS, MD and PhD students. Practical aspects of pharmacology are covered in traditional extemporaneous pharmacy and prescription writing for common diseases. This is included keeping in view of rational drug use and the implication of Pharmacoeconomics. In clinical skill training lab, students are trained in different clinical skills related to drug dosing and administration through mannequins & simulation as per new MCI curriculum.

Besides teaching, students are also trained for detecting, analysing and reporting Adverse Drug Reaction (ADR) as a part of curriculum. The Department is committed to provide best quality and clinically oriented information to MBBS students to make them into rational prescribers.

The Department has started MD Pharmacology in 2016 and has got the recognition of the course in year 2019. The department is also in the process to start DM Clinical Pharmacology course.

Faculty:-

Senior Residents:

Junior Residents:

Scientists:

Patient Care:-

1. ADR Monitoring Centre (AMC): The tireless effort of Professor (Dr.) Harihar Dikshit to establish ADR monitoring centre under Pharmacovigilance Programme of India made the Department of Pharmacology, IGIMS in 2012 to start Adverse Drug Reaction monitoring program which of course is first in the state and is also one of the milestone for the Institute. The centre is also receiving the ADR reports from the different hospitals of the states. AMC of the Institute has been awarded as the best AMC of India for the year 2015-16 by Indian Pharmacopoeia Commission, Ministry of Health & Family welfare.
2. Pulmonary function test: Department has started clinical services, Pulmonary Function test, for the patient on 26.08.2016. Till date over 1600 Pulmonary Function Tests have been done.
3. 24×7 Drug & Poison Information Centre is going to start soon.
4. Future plans - Therapeutic Drug Monitoring unit in the hospital under the Department of Pharmacology.

Infrastructure & Facilities:-

1. Experimental Pharmacology cum CAL (computer assisted learning) or e-lab: On 5thSept, 2014 the CAL (computer assisted learning) Lab was established with 16 computers using the most modern software animal simulator which of course is first in Bihar and Jharkhand. This boosts up the understanding & knowledge about the subject by the undergraduate and PG students along with non – sacrificing of the animals for experimental purpose as directed by the Medical Council of India.

2. Clinical Pharmacy Lab: A well-equipped clinical pharmacy lab with well-trained pharmacist is running by the department. The modern way of teaching to the medical graduates makes it relevant in the present scenario.
3. Research Lab: A well-equipped Research Lab for carrying out the research in the field of Neuropharmacology, Psychopharmacology, Cardio-vascular pharmacology, Respiratory pharmacology, molecular pharmacology and pharmacogenomics is recently being established. Instrument available in the Research Lab are:

4. Clinical Pharmacology Lab: A modern Clinical Pharmacology Lab with modern instruments is available to carry out research of drugs in humans.

Name of equipment:

• Ambu bag and mask
• B.P. Apparatus
• Bicycle Ergometer (Digital)
• Digital Spirometer
• Nebulizer-diaphragm type
• Peak Flow Meter
• Stethoscope

5. Clinical Skill Training Lab: It has 10 mannequins with accessories to teach some basic clinical skills to students. Students are trained in different clinical skills related to drug dosing, administration and procedures through simulation.

6. Museum: The Department has a well-designed Museum with beautiful glass shelves to display drugs & herbal medicine. A separate section depicting the history of medicine through various charts and photographs of great scientist of all times is present in the gallery of the department.

 List of Items

• Drug samples: 295
• Herbal medicines: 18
• Charts: 43
• Photographs of Scientists: 40
• Photographs of Herbs: 70
• Photographs of ADR: 4
• History of Medicine charts: 7
• Models: 13

7. Library: A well-stocked library with more than 250 books and over 254 volumes of scientific journals of different field. The department is free Wi-Fi zone which helps the faculty members and students to get instant access to internet for educational purpose. Free access to UpToDate and Lexicomp is provided to all faculty members and residents in the department.
8. Herbal Garden: A Herbal Garden of Institute is under the department where different types of herbal plants are grown in the natural environment. Some of the common herbal plants are also maintained in the department premises. Constant efforts are undergoing to think about the possible utilisation of the herbal garden in the therapeutics by the department.
9. Central Animal House Facility: Well-equipped and functioning central animal house facility is under the Department of Pharmacology. Many research projects on small animals have been completed as well as some are still ongoing as per CPSCEA guidelines. Postgraduate and PhD students of this institute are using this facility for educational purpose.

 Awards & Honors:

ADR Monitoring Centre of the IGIMS, has been awarded as the best AMC by Pharmacovigilance Programme of India for the year 2015-16.

Recent Achievements

1. Organized National conference -The Dept of Pharmacology had organised ISRPTCON2018 (Indian Society for Rational Pharmacotherapeutics) in the November 2018 at IGIMS.
2. Organized National conference - The Dept of Pharmacology had organised 50^th Annual Inaugural Golden Jubilee Conference of Indian Pharmacological Society (AIGJCONIPS2017) held on date 13^th-15^th February 2017 at IGIMS, Patna.
3. Nominated as one of 15 centres for ICMR task force project on ‘Rational Use of Medicine under National Virtual Centre for Clinical Pharmacology for the purpose of prescription research, preparation of prescribing skill training for interns and Indian Medical Graduates (IMG) and implementing rational use of drugs.
4. Social Awareness: Nukkad Natak  on Antimicrobial Resistance and Adverse Drug Reactions.

Research: ­-

The Department is having a thurst for the clinical research. The Department has organised several CMEs, workshops and conferences to inspire and train faculties and residents for implementing new ideas in carrying out further research.

Ongoing:

1. Study to evaluate awareness about Pharmacovigilance amongst clinician and other health professionals in tertiary care hospital of Bihar. Purnendu Arya, Harihar Dikshit, Hitesh Mishra
2. Drug utilization study and Adverse Drug Monitoring Psychotropic Drugs in tertiary care Hospital of Bihar. Raushan Kumar Ranjan, Lalit Mohan, Rajesh Kumar, Manish Kumar
3. Comparative study of efficacy and safety of linagliptin and insulin in patient of type 2 diabetes and CKD {grade 3-5} in tertiary care hospital of Bihar. Saajid Hameed, Harihar Dikshit, Ved Prakash, Om Kumar
4. Drug utilization study and spontaneous adverse drug event reporting of anticancer drugs in tertiary care hospital of Bihar. Pankaj Kumar, Lalit Mohan, Avinash Pandey, Manish Kumar
5. Evaluation of the prescription pattern of drugs in different OPDs of a tertiary care hospital. Dr Harihar Dikshit, Dr Hitesh Mishra, Dr Sukalyan Saha Roy, Dr Sudhir Kumar, Dr Shambhavi Sharan, Dr Archana Sinha, Dr Sanjay Kumar, Dr Saket Sharma, Dr Sarita Mishra
6. Perception of interns regarding online (learning and assessment) prescribing skills program. Dr Harihar Dikshit, Dr Hitesh Mishra, Dr Sukalyan Saha Roy, Dr Sudhir Kumar, Dr Shambhavi Sharan, Dr Archana Sinha, Dr Sanjay Kumar, Dr Saket Sharma, Dr Sarita Mishra
7. Comparative study to assess the efficacy and safety of Metformin and combination of Metformin with Ranolazine in Glycaemic control of Type 2 Diabetes Patients in tertiary care Hospital of Bihar. Nidhi Kumari, Harihar Dikshit, Ved Prakash, Hitesh Mishra
8. Comparative study Tamsulosin and combination therapy of Tamsulosin with Tadalafil in medical expulsive therapy in patient of ureteric stone in tertiary care Hospital of Bihar. Arun Kumar, Lallit Mohan, Vijay Kumar, Manish Kumar
9. Prescription pattern and safety of immunosuppressive drugs in patient of renal transplant in IGIMS patna, An observational and prospective study. Saajid Hameed, Shambhu Kumar Yadav, Sukalyan Saha Roy, Manish Kumar, Hitesh Mishra, Lalit Mohan, Harihar Dikshit
10. To evaluate the hyperalgesic effect of sitagliptin in albino mice. Rajni Kumari¹, Dr. Lalit Mohan², Dr. Manish Kumar³, Dr. Hitesh Mishra⁴, Prof. (Dr.) Harihar Dikshit⁵, Dr. Akash Chandra⁶, Dr. Lalit Kumar⁷, Dr.Arshana Tabassum⁸
11. Evaluation of hyperalgesic activity of oral lansoprazole in albino mice Dr. Akash Chandra¹, Dr. Lalit Mohan², Dr. Manish Kumar³, Dr. Hitesh Mishra⁴, Prof. (Dr.) Harihar Dikshit ⁵, Dr. Lalit Kumar⁶, Dr.Arshana Tabassum⁷
12. Interaction study of Apigen with Diclofenac in experimental model of inflammation in rat. Arka Mandal, Prof (Dr) Harihar Dikshit, Prof (Dr) Lalit Mohan, Prof (Dr) Avanish Kumar, Dr Hitesh Mishra, Dr Manish Kumar
13. Role of Corneal MicroRNA in Bacterial keratitis mouse model. Dr Lalan kumar arya, Dr Bibhuti Prasad Sinha, Dr Rakhi Kusumesh, Dr Manoj Kumar, Dr Namarta Kumari
14. Acute and sub-chronic toxicity study of Swarna Prasham in rodents. Dr. Pankaj Prabhakar, Prof. N.R. Biswas, Prof. (Dr.) Harihar Dikshit, Prof. (Dr.) Bipin Kusmar, Dr. Manish Kumar, Dr. Manoj Kumar.
15. Evaluation of the effect of Bacopa monnieri (Linn.) and Terminalia belerica (Roxb.) in experimental non-alcoholic fatty liver disease in rats.Dr. Pankaj Prabhakar, Prof. (Dr.) Harihar Dikshit, Dr. Manish Kumar, Prof. (Dr.) Suman Kundu.
16. Evaluation of the effect of indigenous medicinal plants against high fructose and high fat diet-induced experimental nonalcoholic fatty liver disease in rats. Dr. Pankaj Prabhakar, Prof. (Dr.) Harihar Dikshit, Prof. (Dr.) Suman Kundu,
17. Evaluation and comparison of the effect of budding leaves of Clerodendrum infortunatum and metformin in streptozotocin-induccd diabetes in rats. Dr. Manish Kumar

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